HPLC Column, HPS Silica, 5um, 4.6mm ID x 100mm Length, 120A. Cogent Brand. 1 EA.
Additional Info:
75001-10P Cogent HPS Silica™ HPLC Column is packed with high‑purity, unmodified silica, delivering consistent and reproducible performance for normal phase chromatography and USP L3 classified methods.
Because the stationary phase is not chemically bonded, it provides strong, direct interactions with polar and hydrophilic compounds, making it highly effective for fats, lipids, and other polar analytes.
This proprietary HPS Silica™ has been trusted by laboratories for many years as a premium, cost‑effective alternative to established silica products such as Inertsil® and Luna®, delivering dependable selectivity and long‑term reproducibility.
The 5 µm particle size offers a balance of efficiency and durability, allowing higher flow rates with lower system backpressure, making it ideal for routine analytical use on standard HPLC systems.
100 mm Length – Balanced Resolution for Normal Phase HPLC
The 100 mm column length provides increased resolving power without excessive run times.
Greater resolution than 50 mm columns
Improved separation of closely related compounds
Efficient run times for routine and QC workflows
✅ Recommended for applications where moderate resolution improvement is needed
4.6 mm ID – Standard Analytical Format
Designed for 4.6 mm ID analytical columns
Compatible with standard HPLC systems
Higher sample loading capacity
Ideal for routine analytical and QC methods
✅ Recommended for general-purpose HPLC and compendial methods
Flow Rate & System Requirements (4.6 mm ID, 5 µm)
✅ Compatible with standard HPLC systems
Typical flow rate range: ~1.0 – 1.5 mL/min
Lower backpressure compared to smaller particle sizes
Suitable for routine analytical separations
Compatible with UV and other standard detectors
✅ Best Practice: Optimize mobile phase composition for consistent normal phase retention
Why Choose HPS Silica™ Columns
High‑Purity Unmodified Silica
Ideal for normal phase chromatography
Strong retention of polar compounds
USP L3 Compatibility
Suitable for compendial methods
Reliable alternative to legacy silica columns
Reproducible Performance
Consistent selectivity
Proven reliability in long‑term use
Performance Advantages
Lower Backpressure (5 µm Particles)
Enables higher flow rates
Compatible with conventional systems
Fast Equilibration
Reduces analysis cycle time
Effective Polar Retention
Ideal for lipids, fats, and hydrophilic analytes
Typical Applications
Fats and lipid analysis
Normal phase HPLC separations
Polar compound analysis
USP L3 analytical methods
Food, pharmaceutical, and chemical testing
Important Usage Notes
Designed for normal phase chromatography conditions
Use appropriate non‑polar mobile phases
Ensure adequate equilibration for reproducible retention
Follow standard silica handling and storage procedures